› 2q53

X-ray diffraction
2.01Å resolution

Ensemble refinement of the crystal structure of uncharacterized protein loc79017 from Homo sapiens

Released:
DOI: 10.2210/pdb2q53/pdb
PDB entry 2q53 coloured by chain, ensemble of 4 models, front view.
PDB entry 2q53 coloured by chain, ensemble of 4 models, side view.
PDB entry 2q53 coloured by chain, ensemble of 4 models, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of Homo sapiens protein LOC79017.
Bae E, Bingman CA, Aceti DJ, Phillips GN
Proteins 70 588-91 (2008)
PMID: 17932939

Function and Biology Details

Reaction catalysed: 
Alpha-(gamma-L-glutamyl)-L-amino acid = alpha-L-amino acid + 5-oxo-L-proline
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130885 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gamma-glutamylcyclotransferase Chains: A, B
Molecule details ›
Chains: A, B
Length: 188 amino acids
Theoretical weight: 21.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O75223 (Residues: 2-188; Coverage: 100%)
Gene names: C7orf24, CRF21, GGCT
Sequence domains: AIG2-like family
Structure domains: Gamma-glutamyl cyclotransferase-like

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 8 x MSE

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 35.052Å b: 100.138Å c: 102.498Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.189 0.189 0.235
Expression system: Escherichia coli

Quick links

Citations

1 mention without citation

Structure and function of allophanate hydrolase.
Fan et al. (2013)