› 2q60

X-ray diffraction
2.9Å resolution

Crystal structure of the ligand binding domain of polyandrocarpa misakiensis rxr in tetramer in absence of ligand

Released:
DOI: 10.2210/pdb2q60/pdb
PDB entry 2q60 coloured by chain, front view.
PDB entry 2q60 coloured by chain, side view.
PDB entry 2q60 coloured by chain, top view.
Source organism: Polyandrocarpa misakiensis
Primary publication:
Crystal structure of the ligand-binding domain of the retinoid X receptor from the ascidian Polyandrocarpa misakiensis.
Borel F, de Groot A, Juillan-Binard C, de Rosny E, Laudet V, Pebay-Peyroula E, Fontecilla-Camps JC, Ferrer JL
Proteins 74 538-42 (2009)
PMID: 19004016

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193640 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Retinoid X receptor Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 258 amino acids
Theoretical weight: 29.07 KDa
Source organism: Polyandrocarpa misakiensis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UAF1 (Residues: 103-337; Coverage: 65%)
Gene name: PmRXR
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: P212121
Unit cell:
a: 82.26Å b: 96.12Å c: 151.72Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.272 0.269 0.325
Expression system: Escherichia coli

Quick links

Citations

3 citation in other articles

Developmental expression of a molluscan RXR and evidence for its novel, nongenomic role in growth cone guidance.
Carter et al. (2010)
2 more

2 mentions without citation

The retinoid X receptors and their ligands.
Dawson et al. (2012)
1 more