2r52

X-ray diffraction
2.5Å resolution

Crystal structure analysis of Bone Morphogenetic Protein-6 (BMP-6)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-149503 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bone morphogenetic protein 6 Chains: A, B
Molecule details ›
Chains: A, B
Length: 143 amino acids
Theoretical weight: 16.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P22004 (Residues: 375-513; Coverage: 28%)
Gene names: BMP6, VGR
Sequence domains: Transforming growth factor beta like domain
Structure domains: Cystine-knot cytokines

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P3121
Unit cell:
a: 97.655Å b: 97.655Å c: 85.048Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.245 0.235 0.27
Expression system: Escherichia coli BL21(DE3)