› 2r7i

X-ray diffraction
3Å resolution

Crystal structure of catalytic subunit of protein kinase CK2

Released:
DOI: 10.2210/pdb2r7i/pdb
PDB entry 2r7i coloured by chain, front view.
PDB entry 2r7i coloured by chain, side view.
PDB entry 2r7i coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Crystal structures of catalytic and regulatory subunits of rat protein kinase CK2
Zhou W, Qin X, Yan X, Xie X, Li L, Fang S, Long J, Adelman J, Tang W-J, Shen Y
Chin. Sci. Bull. 54 220-226 (2009)

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148510 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Casein kinase II subunit alpha Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 335 amino acids
Theoretical weight: 40.1 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P19139 (Residues: 1-335; Coverage: 86%)
Gene name: Csnk2a1
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand SO4 8 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P43
Unit cell:
a: 127.517Å b: 127.517Å c: 126.406Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.218 0.216 0.257
Expression system: Escherichia coli

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