› 2rli

Solution NMR

Solution structure of Cu(I) human Sco2

Released:
DOI: 10.2210/pdb2rli/pdb
PDB entry 2rli coloured by chain, ensemble of 31 models, front view.
PDB entry 2rli coloured by chain, ensemble of 31 models, side view.
PDB entry 2rli coloured by chain, ensemble of 31 models, top view.
Source organism: Homo sapiens
Primary publication:
A structural characterization of human SCO2.
Banci L, Bertini I, Ciofi-Baffoni S, Gerothanassis IP, Leontari I, Martinelli M, Wang S
Structure 15 1132-40 (2007)
PMID: 17850752

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129144 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein SCO2 homolog, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 171 amino acids
Theoretical weight: 19.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O43819 (Residues: 100-266; Coverage: 63%)
Gene name: SCO2
Sequence domains: SCO1/SenC
Structure domains: Glutaredoxin

Ligands and Environments

1 bound ligand:
Ligand CU1 1 x CU1
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: molecular dynamics
Expression system: Escherichia coli

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Citations

13 review citations

Copper metallochaperones.
Robinson et al. (2010)
12 more

5 mentions without citation

Mitochondrial cytochrome c oxidase biogenesis: Recent developments.
Timón-Gómez et al. (2018)
4 more