› 2roq

Solution NMR

Solution Structure of the thiolation-thioesterase di-domain of enterobactin synthetase component F

Released:
DOI: 10.2210/pdb2roq/pdb
PDB entry 2roq coloured by chain, ensemble of 20 models, front view.
PDB entry 2roq coloured by chain, ensemble of 20 models, side view.
PDB entry 2roq coloured by chain, ensemble of 20 models, top view.
Source organism: Escherichia coli
Primary publication:
Dynamic thiolation-thioesterase structure of a non-ribosomal peptide synthetase.
Frueh DP, Arthanari H, Koglin A, Vosburg DA, Bennett AE, Walsh CT, Wagner G
Nature 454 903-6 (2008)
PMID: 18704088

Function and Biology Details

Reactions catalysed: 
(1a) ATP + L-serine = diphosphate + (L-seryl)adenylate
6 ATP + 3 2,3-dihydroxybenzoate + 3 L-serine = enterobactin + 6 AMP + 6 diphosphate
Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145843 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Enterobactin synthase component F Chain: A
Molecule details ›
Chain: A
Length: 343 amino acids
Theoretical weight: 37.52 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P11454 (Residues: 960-1293; Coverage: 26%)
Gene names: JW0578, b0586, entF
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Escherichia coli

Quick links

Citations

29 review citations

Chemistry and biology of siderophores.
Hider et al. (2010)
28 more

9 mentions without citation

Structural insights into nonribosomal peptide enzymatic assembly lines.
Koglin et al. (2009)
8 more