› 2rq1

Solution NMR

Solution structure of the 4.1R FERM alpha lobe domain

Released:
DOI: 10.2210/pdb2rq1/pdb
PDB entry 2rq1 coloured by chain, ensemble of 20 models, front view.
PDB entry 2rq1 coloured by chain, ensemble of 20 models, side view.
PDB entry 2rq1 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure and glycophorin C binding studies of the protein 4.1R FERM alpha-lobe domain.
Kusunoki H, Kohno T
Proteins 76 255-60 (2009)
PMID: 19338061

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145690 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein 4.1 Chain: A
Molecule details ›
Chain: A
Length: 109 amino acids
Theoretical weight: 12.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P11171 (Residues: 292-396; Coverage: 12%)
Gene names: E41P, EPB41
Sequence domains: FERM central domain
Structure domains: Acyl-CoA Binding Protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

2 review citations

The Protein 4.1 family: hub proteins in animals for organizing membrane proteins.
Baines et al. (2014)
1 more

1 mention without citation

The dipeptidyl peptidase IV inhibitors vildagliptin and K-579 inhibit a phospholipase C: a case of promiscuous scaffolds in proteins.
Chakraborty et al. (2013)