› 2rqp

Solution NMR

The Solution Structure of Heterochromatin Protein 1-Binding Protein 74 Histone H1 like domain

Released:
DOI: 10.2210/pdb2rqp/pdb
PDB entry 2rqp coloured by chain, ensemble of 12 models, front view.
PDB entry 2rqp coloured by chain, ensemble of 12 models, side view.
PDB entry 2rqp coloured by chain, ensemble of 12 models, top view.
Source organism: Homo sapiens
Primary publication:
The middle region of an HP1-binding protein, HP1-BP74, associates with linker DNA at the entry/exit site of nucleosomal DNA.
Hayashihara K, Uchiyama S, Shimamoto S, Kobayashi S, Tomschik M, Wakamatsu H, No D, Sugahara H, Hori N, Noda M, Ohkubo T, Zlatanova J, Matsunaga S, Fukui K
J Biol Chem 285 6498-507 (2010)
PMID: 20042602

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178279 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Heterochromatin protein 1-binding protein 3 Chain: A
Molecule details ›
Chain: A
Length: 88 amino acids
Theoretical weight: 9.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5SSJ5 (Residues: 153-237; Coverage: 15%)
Gene name: HP1BP3
Sequence domains: linker histone H1 and H5 family
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

16 citation in other articles

DNA methylation: superior or subordinate in the epigenetic hierarchy?
Jin et al. (2011)
15 more

3 mentions without citation

The middle region of an HP1-binding protein, HP1-BP74, associates with linker DNA at the entry/exit site of nucleosomal DNA.
Hayashihara et al. (2010)
2 more