› 2rr6

Solution NMR

Solution structure of the leucine rich repeat of human acidic leucine-rich nuclear phosphoprotein 32 family member B

Released:
DOI: 10.2210/pdb2rr6/pdb
PDB entry 2rr6 coloured by chain, ensemble of 20 models, front view.
PDB entry 2rr6 coloured by chain, ensemble of 20 models, side view.
PDB entry 2rr6 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of histone chaperone ANP32B: interaction with core histones H3-H4 through its acidic concave domain.
Tochio N, Umehara T, Munemasa Y, Suzuki T, Sato S, Tsuda K, Koshiba S, Kigawa T, Nagai R, Yokoyama S
J Mol Biol 401 97-114 (2010)
PMID: 20538007

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187720 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Acidic leucine-rich nuclear phosphoprotein 32 family member B Chain: A
Molecule details ›
Chain: A
Length: 168 amino acids
Theoretical weight: 18.84 KDa
Source organism: Homo sapiens
Expression system: cell-free synthesis
UniProt:
  • Canonical: Q92688 (Residues: 1-161; Coverage: 64%)
Gene names: ANP32B, APRIL, PHAPI2
Sequence domains: Leucine Rich repeats (2 copies)
Structure domains: Ribonuclease Inhibitor

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, simulated annealing
Expression system: cell-free synthesis

Quick links

Citations

4 review citations

Histone variants: dynamic punctuation in transcription.
Weber et al. (2014)
3 more

2 mentions without citation

Structural and functional analysis of novel human cytochrome C targets in apoptosis.
Martínez-Fábregas et al. (2014)
1 more