2v7d

X-ray diffraction
2.5Å resolution

14-3-3 protein zeta in complex with Thr758 phosphorylated integrin beta2 peptide

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-138499 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
14-3-3 protein zeta/delta Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 247 amino acids
Theoretical weight: 27.92 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P63103 (Residues: 1-245; Coverage: 100%)
Gene name: YWHAZ
Sequence domains: 14-3-3 protein
Structure domains: 14-3-3 domain
Integrin beta-2 Chains: P, Q, R, S
Molecule details ›
Chains: P, Q, R, S
Length: 10 amino acids
Theoretical weight: 1.13 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P05107 (Residues: 755-764; Coverage: 1%)
Gene names: CD18, ITGB2, MFI7

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-3
Spacegroup: P65
Unit cell:
a: 94.92Å b: 94.92Å c: 233.6Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.228 0.228 0.273
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided