Function and Biology Details
Reaction catalysed:
S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- tRNA (guanine-N-7) methyltransferase, Trmb type
- WD40 repeat
- S-adenosyl-L-methionine-dependent methyltransferase superfamily
- tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit
- tRNA (guanine-N-7) methyltransferase catalytic subunit Trm8, eukaryote
- WD40/YVTN repeat-like-containing domain superfamily
- WD40-repeat-containing domain superfamily
Structure analysis Details
Assemblies composition:
Assembly name:
tRNA (guanine-N(7)-)-methyltransferase (preferred)
PDBe Complex ID:
PDB-CPX-169945 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82
Molecule details ›
Chains: B, D
Length: 450 amino acids
Theoretical weight: 51.38 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
Length: 450 amino acids
Theoretical weight: 51.38 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
- Canonical:
Q03774 (Residues: 1-444; Coverage: 100%)
tRNA (guanine-N(7)-)-methyltransferase
Molecule details ›
Chains: E, F
Length: 254 amino acids
Theoretical weight: 29.8 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
Sequence domains: Putative methyltransferase
Structure domains: Vaccinia Virus protein VP39
Length: 254 amino acids
Theoretical weight: 29.8 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
- Canonical: Q12009 (Residues: 39-286; Coverage: 87%)
Sequence domains: Putative methyltransferase
Structure domains: Vaccinia Virus protein VP39
