› 2vsp

X-ray diffraction
2.41Å resolution

Crystal structure of the fourth PDZ domain of PDZ domain-containing protein 1

Released:
DOI: 10.2210/pdb2vsp/pdb
PDB entry 2vsp coloured by chain, front view.
PDB entry 2vsp coloured by chain, side view.
PDB entry 2vsp coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Yue WW, Shafqat N, Pilka ES, Johansson C, Murray JW, Elkins J, Roos A, Cooper C, Phillips C, Salah E, von Delft F, Doyle D, Edwards A, Wikstrom M, Arrowsmith C, Bountra C, Oppermann U

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178299 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Na(+)/H(+) exchange regulatory cofactor NHE-RF3 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 91 amino acids
Theoretical weight: 9.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5T2W1 (Residues: 375-461; Coverage: 17%)
Gene names: CAP70, NHERF3, PDZD1, PDZK1
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: R3
Unit cell:
a: 99.327Å b: 99.327Å c: 97.114Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.217 0.215 0.267
Expression system: Escherichia coli BL21(DE3)

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