› 2vsy

X-ray diffraction
2.1Å resolution

Xanthomonas campestris putative OGT (XCC0866), apostructure

Released:
DOI: 10.2210/pdb2vsy/pdb
PDB entry 2vsy coloured by chain, front view.
PDB entry 2vsy coloured by chain, side view.
PDB entry 2vsy coloured by chain, top view.
Source organism: Xanthomonas campestris pv. campestris str. ATCC 33913
Primary publication:
Structural insights into mechanism and specificity of O-GlcNAc transferase.
Clarke AJ, Hurtado-Guerrero R, Pathak S, Schüttelkopf AW, Borodkin V, Shepherd SM, Ibrahim AF, van Aalten DM
EMBO J 27 2780-8 (2008)
PMID: 18818698

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185736 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
O-GlcNAc transferase C-terminal domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 568 amino acids
Theoretical weight: 61.42 KDa
Source organism: Xanthomonas campestris pv. campestris str. ATCC 33913
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8PC69 (Residues: 1-568; Coverage: 100%)
Gene name: XCC0866
Sequence domains:
Structure domains:

Ligands and Environments

4 bound ligands:
Ligand NHE 3 x NHE
Ligand PEG 2 x PEG
Ligand PR 3 x PR
Ligand CL 2 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P212121
Unit cell:
a: 81.523Å b: 100.096Å c: 156.274Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.194 0.193 0.236
Expression system: Escherichia coli

Quick links

Citations

32 review citations

Cross talk between O-GlcNAcylation and phosphorylation: roles in signaling, transcription, and chronic disease.
Hart et al. (2011)
31 more

3 mentions without citation

Structural insights into mechanism and specificity of O-GlcNAc transferase.
Clarke et al. (2008)
2 more