› 2vwd

X-ray diffraction
2.25Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191528 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glycoprotein G Chains: A, B
Molecule details ›
Chains: A, B
Length: 420 amino acids
Theoretical weight: 47.2 KDa
Source organism: Henipavirus nipahense
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9IH62 (Residues: 183-602; Coverage: 70%)
Gene name: G
Sequence domains: Haemagglutinin-neuraminidase
Structure domains: Neuraminidase

Ligands and Environments

3 bound ligands:
Ligand GBL 8 x GBL
Ligand NAG 10 x NAG
Ligand CL 2 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P21
Unit cell:
a: 71.633Å b: 86.936Å c: 82.903Å
α: 90° β: 108.32° γ: 90°
R-values:
R R work R free
0.175 0.172 0.221
Expression system: Homo sapiens

Quick links

Citations

23 review citations

The HIV glycan shield as a target for broadly neutralizing antibodies.
Doores KJ. (2015)
22 more

11 mentions without citation

Cells under siege: viral glycoprotein interactions at the cell surface.
Bowden et al. (2011)
10 more