› 2vxp

X-ray diffraction
2.5Å resolution

The fourth FAS1 domain structure of human Bigh3

Released:
DOI: 10.2210/pdb2vxp/pdb
PDB entry 2vxp coloured by chain, front view.
PDB entry 2vxp coloured by chain, side view.
PDB entry 2vxp coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Yoo J-H, Cho H-S

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172330 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transforming growth factor-beta-induced protein ig-h3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 132 amino acids
Theoretical weight: 14.26 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q15582 (Residues: 502-633; Coverage: 20%)
Gene names: BIGH3, TGFBI
Sequence domains: Fasciclin domain
Structure domains: FAS1 domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 4A
Spacegroup: P65
Unit cell:
a: 62.934Å b: 62.934Å c: 143.29Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.27 0.27 0.285
Expression system: Escherichia coli BL21(DE3)

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