Function and Biology Details
Reactions catalysed:
ATP + 5'-dephospho-DNA = ADP + 5'-phospho-DNA
A 3'-phosphopolynucleotide + H(2)O = a polynucleotide + phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148467 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Bifunctional polynucleotide phosphatase/kinase
Molecule details ›
Chains: A, B
Length: 113 amino acids
Theoretical weight: 12.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: FHA domain
Structure domains: Tumour Suppressor Smad4
Length: 113 amino acids
Theoretical weight: 12.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q96T60 (Residues: 1-110; Coverage: 21%)
Sequence domains: FHA domain
Structure domains: Tumour Suppressor Smad4
DNA repair protein XRCC1
Molecule details ›
Chains: C, D
Length: 8 amino acids
Theoretical weight: 1.02 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 8 amino acids
Theoretical weight: 1.02 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P18887 (Residues: 515-522; Coverage: 1%)
