› 2wfs

Electron Microscopy
12Å resolution

Fitting of influenza virus NP structure into the 9-fold symmetryzed cryoEM reconstruction of an active RNP particle.

Released:
DOI: 10.2210/pdb2wfs/pdb
PDB entry 2wfs coloured by chain, front view.
PDB entry 2wfs coloured by chain, side view.
PDB entry 2wfs coloured by chain, top view.
Source organism: Influenza A virus
Primary publication:
The structure of a biologically active influenza virus ribonucleoprotein complex.
Coloma R, Valpuesta JM, Arranz R, Carrascosa JL, Ortín J, Martín-Benito J
PLoS Pathog 5 e1000491 (2009)
PMID: 19557158
Related structures: EMD-1603

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137051 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoprotein Chains: A, B, C, D, E, F, G, H, I
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I
Length: 499 amino acids
Theoretical weight: 56.81 KDa
Source organism: Influenza A virus
Expression system: Chlorocebus aethiops
UniProt:
  • Canonical: P03466 (Residues: 8-498; Coverage: 99%)
Gene name: NP
Sequence domains: Influenza virus nucleoprotein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 12Å
Relevant EMDB volumes: EMD-1603
Expression system: Chlorocebus aethiops

Quick links

Citations

27 review citations

Structures of influenza A proteins and insights into antiviral drug targets.
Das et al. (2010)
26 more

4 mentions without citation

The structure of a biologically active influenza virus ribonucleoprotein complex.
Coloma et al. (2009)
3 more