› 2wlk

X-ray diffraction
2.8Å resolution

STRUCTURE OF THE ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL FROM MAGNETOSPIRILLUM MAGNETOTACTICUM

Released:
DOI: 10.2210/pdb2wlk/pdb
PDB entry 2wlk coloured by chain, front view.
PDB entry 2wlk coloured by chain, side view.
PDB entry 2wlk coloured by chain, top view.
Source organism: Magnetospirillum magnetotacticum
Primary publication:
Domain reorientation and rotation of an intracellular assembly regulate conduction in Kir potassium channels.
Clarke OB, Caputo AT, Hill AP, Vandenberg JI, Smith BJ, Gulbis JM
Cell 141 1018-29 (2010)
PMID: 20564790

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-112991 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Inward rectifier potassium channel Kirbac3.1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 301 amino acids
Theoretical weight: 33.78 KDa
Source organism: Magnetospirillum magnetotacticum
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: D9N164 (Residues: 1-295; Coverage: 100%)
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand K 5 x K
Ligand CL 1 x CL
Ligand SPM 1 x SPM
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21212
Unit cell:
a: 105.76Å b: 107.53Å c: 89.65Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.248 0.247 0.28
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

14 review citations

GPCR mediated regulation of synaptic transmission.
Betke et al. (2012)
13 more

3 mentions without citation

Structure of potassium channels.
Kuang et al. (2015)
2 more