› 2wmd

X-ray diffraction
2Å resolution

Crystal structure of NmrA-like family domain containing protein 1 in complex with NADP and 2-(4-chloro-phenylamino)-nicotinic acid

Released:
DOI: 10.2210/pdb2wmd/pdb
PDB entry 2wmd coloured by chain, front view.
PDB entry 2wmd coloured by chain, side view.
PDB entry 2wmd coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Bhatia C, Pilka E, Niesen F, Yue WW, Ugochukwu E, Savitsky P, Hozjan V, Roos AK, Filippakopoulos P, von Delft F, Heightman T, Arrowsmith C, Weigelt J, Edwards A, Bountra C, Oppermann U

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190758 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NmrA-like family domain-containing protein 1 Chain: A
Molecule details ›
Chain: A
Length: 299 amino acids
Theoretical weight: 33.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9HBL8 (Residues: 1-298; Coverage: 100%)
Gene names: HSCARG, NMRAL1
Sequence domains: NmrA-like family
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand ZZ0 1 x ZZ0
Ligand NAP 1 x NAP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Unit cell:
a: 57.722Å b: 79.734Å c: 86.362Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.202 0.248
Expression system: Escherichia coli BL21(DE3)

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