› 2wql

X-ray diffraction
2.7Å resolution

CRYSTAL STRUCTURE OF THE MAJOR CARROT ALLERGEN DAU C 1

Released:
DOI: 10.2210/pdb2wql/pdb
PDB entry 2wql coloured by chain, front view.
PDB entry 2wql coloured by chain, side view.
PDB entry 2wql coloured by chain, top view.
Source organism: Daucus carota
Primary publication:
Structure of the major carrot allergen Dau c 1.
Marković-Housley Z, Basle A, Padavattan S, Maderegger B, Schirmer T, Hoffmann-Sommergruber K
Acta Crystallogr D Biol Crystallogr 65 1206-12 (2009)
PMID: 19923716

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126440 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Major allergen Dau c 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 154 amino acids
Theoretical weight: 16.09 KDa
Source organism: Daucus carota
Expression system: Escherichia coli
UniProt:
  • Canonical: O04298 (Residues: 1-154; Coverage: 100%)
Sequence domains: Pathogenesis-related protein Bet v 1 family
Structure domains: Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4

Ligands and Environments

3 bound ligands:
Ligand P4C 4 x P4C
Ligand PEG 6 x PEG
Ligand CL 16 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P4132
Unit cell:
a: 189.948Å b: 189.948Å c: 189.948Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.222 0.221 0.237
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Structural and functional aspects of PR-10 proteins.
Fernandes et al. (2013)
1 more

8 mentions without citation

Structure of allergens and structure based epitope predictions.
Dall'antonia et al. (2014)
7 more