› 2wsr

X-ray diffraction
1.65Å resolution

MONOTIM MUTANT RMM0-1, MONOMERIC FORM.

Released:
DOI: 10.2210/pdb2wsr/pdb
PDB entry 2wsr coloured by chain, front view.
PDB entry 2wsr coloured by chain, side view.
PDB entry 2wsr coloured by chain, top view.
Source organism: Trypanosoma brucei brucei
Entry authors: Rudino-Pinera E, Rojas-Trejo SP, Arreola R, Saab-Rincon G, Soberon X, Horjales E

Function and Biology Details

Reaction catalysed: 
D-glyceraldehyde 3-phosphate = glycerone phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138175 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Triosephosphate isomerase, glycosomal Chain: A
Molecule details ›
Chain: A
Length: 242 amino acids
Theoretical weight: 26.04 KDa
Source organism: Trypanosoma brucei brucei
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P04789 (Residues: 2-250; Coverage: 97%)
Sequence domains: Triosephosphate isomerase
Structure domains: Aldolase class I

Ligands and Environments

2 bound ligands:
Ligand SO4 4 x SO4
Ligand AZI 2 x AZI
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: C2
Unit cell:
a: 84.617Å b: 41.976Å c: 69.512Å
α: 90° β: 108.69° γ: 90°
R-values:
R R work R free
0.216 0.211 0.255
Expression system: Escherichia coli BL21(DE3)

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