Function and Biology Details
Reactions catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Endonucleolytic cleavage to 5'-phosphomonoester.
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Ribonuclease H (preferred)
PDBe Complex ID:
PDB-CPX-146935 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Integrase
Molecule details ›
Chains: A, B, C, D, E, F
Length: 200 amino acids
Theoretical weight: 22.58 KDa
Source organism: Human spumaretrovirus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Integrase core domain
Structure domains: Ribonuclease H-like superfamily/Ribonuclease H
Length: 200 amino acids
Theoretical weight: 22.58 KDa
Source organism: Human spumaretrovirus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P14350 (Residues: 861-1060; Coverage: 18%)
Sequence domains: Integrase core domain
Structure domains: Ribonuclease H-like superfamily/Ribonuclease H
