Function and Biology Details
Biochemical function:
- not assigned
Biological process:
Cellular component:
Sequence domains:
- Bcl-2 family
- Bcl-2-like superfamily
- Apoptosis regulator, Bcl-2
- Apoptosis regulator, Bcl-2 protein, BH4
- Apoptosis regulator, Bcl-2, BH3 motif, conserved site
- Apoptosis regulator, Bcl-2, BH2 motif, conserved site
- Apoptosis regulator, Bcl-2, BH1 motif, conserved site
- Bcl-2, Bcl-2 homology region 1-3
3 more domains
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145307 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Apoptosis regulator Bcl-2
Molecule details ›
Chains: A, B
Length: 207 amino acids
Theoretical weight: 22.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Structure domains: Blc2-like
Length: 207 amino acids
Theoretical weight: 22.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P10415 (Residues: 1-207; Coverage: 87%)
Sequence domains:
Structure domains: Blc2-like
Apoptosis regulator BAX
Molecule details ›
Chains: C, D
Length: 31 amino acids
Theoretical weight: 3.57 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
Length: 31 amino acids
Theoretical weight: 3.57 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
- Canonical: Q07813 (Residues: 52-82; Coverage: 16%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
PAL/PLS BEAMLINE 4A
Spacegroup:
P3121
Expression systems:
- Escherichia coli BL21(DE3)
- Not provided
