› 2xd7

X-ray diffraction
2.09Å resolution

Crystal structure of the macro domain of human core histone H2A

Released:
DOI: 10.2210/pdb2xd7/pdb
PDB entry 2xd7 coloured by chain, front view.
PDB entry 2xd7 coloured by chain, side view.
PDB entry 2xd7 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Vollmar M, Phillips C, Carpenter EP, Muniz JRC, Krojer T, Ugochukwu E, von Delft F, Bountra C, Arrowsmith CH, Weigelt J, Edwards A, Gileadi O

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192803 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Core histone macro-H2A.2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 193 amino acids
Theoretical weight: 20.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9P0M6 (Residues: 177-369; Coverage: 52%)
Gene names: H2AFY2, MACROH2A2
Sequence domains: Macro domain
Structure domains: Leucine Aminopeptidase, subunit E, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: C2
Unit cell:
a: 57.03Å b: 61.64Å c: 242.23Å
α: 90° β: 89.64° γ: 90°
R-values:
R R work R free
0.219 0.217 0.253
Expression system: Escherichia coli BL21(DE3)

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