Assemblies
Multimeric state:
hetero hexamer
Accessible surface area:
46870.32 Å2
Buried surface area:
15358.22 Å2
Dissociation area:
760.28
Å2
Dissociation energy (ΔGdiss):
-3.01
kcal/mol
Dissociation entropy (TΔSdiss):
14.22
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-134725
Macromolecules
Chain: A
Length: 204 amino acids
Theoretical weight: 22.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam: Domain of unknown function (DUF1968)
InterPro:
Length: 204 amino acids
Theoretical weight: 22.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P01848 (Residues: 1-93; Coverage: 66%)
Pfam: Domain of unknown function (DUF1968)
InterPro:
- Immunoglobulin-like domain
- Immunoglobulin-like fold
- Immunoglobulin-like domain superfamily
- Immunoglobulin V-set domain
- Immunoglobulin subtype
- T-cell receptor alpha chain, constant domain
Chain: B
Length: 244 amino acids
Theoretical weight: 27.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam: Immunoglobulin C1-set domain
InterPro:
Length: 244 amino acids
Theoretical weight: 27.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P01850 (Residues: 1-129; Coverage: 73%)
Pfam: Immunoglobulin C1-set domain
InterPro:
- Immunoglobulin-like domain
- Immunoglobulin-like fold
- Immunoglobulin-like domain superfamily
- Immunoglobulin V-set domain
- Immunoglobulin subtype
- Immunoglobulin C1-set
Chain: C
Length: 217 amino acids
Theoretical weight: 25.18 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli K-12
UniProt:
Pfam:
Length: 217 amino acids
Theoretical weight: 25.18 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli K-12
UniProt:
- Canonical: P0A0M0 (Residues: 25-241; Coverage: 100%)
Pfam:
- Staphylococcal/Streptococcal toxin, OB-fold domain
- Staphylococcal/Streptococcal toxin, beta-grasp domain
- Enterotoxin
- Staphylococcal/Streptococcal toxin, OB-fold
- Superantigen, staphylococcal/streptococcal toxin, bacterial
- Staphylococcal/streptococcal toxin, bacterial
- Superantigen toxin, C-terminal
- Staphylococcal/Streptococcal toxin, beta-grasp domain
- Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site
Chain: D
Length: 182 amino acids
Theoretical weight: 21.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam:
InterPro:
Length: 182 amino acids
Theoretical weight: 21.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P01903 (Residues: 26-207; Coverage: 80%)
Pfam:
InterPro:
- Immunoglobulin-like domain
- Immunoglobulin-like fold
- Immunoglobulin-like domain superfamily
- Immunoglobulin C1-set
- MHC class II, alpha/beta chain, N-terminal
- MHC classes I/II-like antigen recognition protein
- MHC class II, alpha chain, N-terminal
- Immunoglobulin/major histocompatibility complex, conserved site
Chain: E
Length: 190 amino acids
Theoretical weight: 22.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam:
InterPro:
Length: 190 amino acids
Theoretical weight: 22.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P01911 (Residues: 30-219; Coverage: 80%)
Pfam:
InterPro:
- Immunoglobulin-like domain
- Immunoglobulin-like fold
- Immunoglobulin-like domain superfamily
- Immunoglobulin C1-set
- MHC class II, alpha/beta chain, N-terminal
- MHC classes I/II-like antigen recognition protein
- Immunoglobulin/major histocompatibility complex, conserved site
- MHC class II, beta chain, N-terminal
Chain: F
Length: 13 amino acids
Theoretical weight: 1.51 KDa
Source organism: Influenza A virus
Expression system: Not provided
UniProt:
Length: 13 amino acids
Theoretical weight: 1.51 KDa
Source organism: Influenza A virus
Expression system: Not provided
UniProt:
- Canonical: Q03909 (Residues: 327-339; Coverage: 2%)