› 2xyb

X-ray diffraction
1.75Å resolution

CRYSTAL STRUCTURE OF A FULLY FUNCTIONAL LACCASE FROM THE LIGNINOLYTIC FUNGUS PYCNOPORUS CINNABARINUS

Released:
DOI: 10.2210/pdb2xyb/pdb
PDB entry 2xyb coloured by chain, front view.
PDB entry 2xyb coloured by chain, side view.
PDB entry 2xyb coloured by chain, top view.
Source organism: Trametes cinnabarina
Entry authors: Piontek K, Choinowski T, Antorini M, Herpoel-Gimbert I, Plattner DA, Sigoillot JC, Asther M, Winterhalter K

Function and Biology Details

Reaction catalysed: 
4 benzenediol + O(2) = 4 benzosemiquinone + 2 H(2)O
Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194110 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (4 distinct):
Laccase Chain: A
Molecule details ›
Chain: A
Length: 497 amino acids
Theoretical weight: 54 KDa
Source organism: Trametes cinnabarina
UniProt:
  • Canonical: Q9UVQ2 (Residues: 22-518; Coverage: 100%)
Gene names: BN946_scf185007.g107, Lac1, lac1
Sequence domains:
Structure domains: Cupredoxins - blue copper proteins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
9 bound ligands:
Ligand CU 4 x CU
Ligand PER 1 x PER
Ligand NAG 1 x NAG
Ligand AS8 1 x AS8
Ligand ACT 1 x ACT
Ligand SO4 2 x SO4
Ligand GOL 4 x GOL
Ligand ZN 8 x ZN
Ligand NA 1 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: C2
Unit cell:
a: 145.296Å b: 62.902Å c: 91.416Å
α: 90° β: 126.7° γ: 90°
R-values:
R R work R free
0.166 0.164 0.208

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