Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- Serine-threonine/tyrosine-protein kinase, catalytic domain
- Tyrosine-protein kinase, active site
- Protein kinase, ATP binding site
- Tyrosine-protein kinase, catalytic domain
- Protein kinase domain
- Protein kinase-like domain superfamily
- Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Tyrosine-protein kinase ABL2 (preferred)
PDBe Complex ID:
PDB-CPX-154850 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein kinase ABL2
Molecule details ›
Chains: A, B, C
Length: 292 amino acids
Theoretical weight: 33.54 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
Sequence domains: Protein tyrosine and serine/threonine kinase
Structure domains:
Length: 292 amino acids
Theoretical weight: 33.54 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
- Canonical:
P42684 (Residues: 279-546; Coverage: 23%)
Sequence domains: Protein tyrosine and serine/threonine kinase
Structure domains:
