Function and Biology Details
Reaction catalysed:
The peptide bond hydrolyzed can be designated -C-|-A-A-X in which C is an S-isoprenylated cysteine residue, A is usually aliphatic and X is the C-terminal residue of the substrate protein, and may be any of several amino acids.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
CAAX prenyl protease 1 homolog and Lamin-A/C (preferred)
PDBe Complex ID:
PDB-CPX-131146 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
CAAX prenyl protease 1 homolog
Molecule details ›
Chains: A, B, D, E
Length: 482 amino acids
Theoretical weight: 55.65 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Structure domains: Metalloproteases ("zincins"), catalytic domain
Length: 482 amino acids
Theoretical weight: 55.65 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
O75844 (Residues: 1-475; Coverage: 100%)
Sequence domains:
Structure domains: Metalloproteases ("zincins"), catalytic domain
Prelamin-A/C
Molecule details ›
Chains: F, G, H, I
Length: 4 amino acids
Theoretical weight: 453 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 4 amino acids
Theoretical weight: 453 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P02545 (Residues: 661-664; Coverage: 1%)
