› 2yxb

X-ray diffraction
1.8Å resolution

Crystal structure of the methylmalonyl-CoA mutase alpha-subunit from Aeropyrum pernix

Released:
DOI: 10.2210/pdb2yxb/pdb
PDB entry 2yxb coloured by chain, front view.
PDB entry 2yxb coloured by chain, side view.
PDB entry 2yxb coloured by chain, top view.
Source organism: Aeropyrum pernix K1
Entry authors: Handa N, Bessho Y, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
(R)-methylmalonyl-CoA = succinyl-CoA
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195450 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
B12-binding domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 161 amino acids
Theoretical weight: 17.98 KDa
Source organism: Aeropyrum pernix K1
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9YBB1 (Residues: 1-161; Coverage: 100%)
Gene name: APE_1686.1
Sequence domains: B12 binding domain
Structure domains: Cobalamin-binding domain

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 6 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B2
Spacegroup: P212121
Unit cell:
a: 42.902Å b: 51.134Å c: 54.564Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.212 0.247
Expression system: Escherichia coli

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