› 2yyo

X-ray diffraction
2Å resolution

Crystal structure of human SPRY domain

Released:
DOI: 10.2210/pdb2yyo/pdb
PDB entry 2yyo coloured by chain, front view.
PDB entry 2yyo coloured by chain, side view.
PDB entry 2yyo coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Kishishita S, Uchikubo-Kamo T, Murayama K, Terada T, Chen L, Fu ZQ, Chrzas J, Shirouzu M, Wang BC, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185488 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SPRY domain-containing protein 3 Chain: A
Molecule details ›
Chain: A
Length: 171 amino acids
Theoretical weight: 18.26 KDa
Source organism: Homo sapiens
Expression system: Cell-free protein synthesis
UniProt:
  • Canonical: Q8NCJ5 (Residues: 46-203; Coverage: 36%)
Gene name: SPRYD3
Sequence domains: SPRY domain
Structure domains: Jelly Rolls

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 3 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P43212
Unit cell:
a: 52.107Å b: 52.107Å c: 108.583Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.218 0.218 0.261
Expression system: Cell-free protein synthesis

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