› 2z1b

X-ray diffraction
3.3Å resolution

Crystal Structure of 5-aminolevulinic acid dehydratase (ALAD) from Mus musculs

Released:
DOI: 10.2210/pdb2z1b/pdb
PDB entry 2z1b coloured by chain, front view.
PDB entry 2z1b coloured by chain, side view.
PDB entry 2z1b coloured by chain, top view.
Source organism: Mus musculus
Entry authors: Xie Y, Wang H, Kawazoe M, Kishishita S, Murayama K, Takemoto C, Terada T, Shirozu M, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
2 5-aminolevulinate = porphobilinogen + 2 H(2)O
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145331 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Delta-aminolevulinic acid dehydratase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 330 amino acids
Theoretical weight: 36.08 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: P10518 (Residues: 1-330; Coverage: 100%)
Gene names: Alad, Lv
Sequence domains: Delta-aminolevulinic acid dehydratase
Structure domains: Aldolase class I

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NW12A
Spacegroup: P6222
Unit cell:
a: 240.92Å b: 240.92Å c: 103.94Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.278 0.278 0.353
Expression system: Not provided

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