› 2zc1

X-ray diffraction
1.9Å resolution

Organophosphorus Hydrolase from Deinococcus radiodurans

Released:
DOI: 10.2210/pdb2zc1/pdb
PDB entry 2zc1 coloured by chain, front view.
PDB entry 2zc1 coloured by chain, side view.
PDB entry 2zc1 coloured by chain, top view.
Source organism: Deinococcus radiodurans
Entry authors: Larsen SD, Hawwa R, Ratia K, Santarsiero BD, Mesecar AD

Function and Biology Details

Reaction catalysed: 
An aryl dialkyl phosphate + H(2)O = dialkyl phosphate + an aryl alcohol
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-193304 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphotriesterase, putative Chain: A
Molecule details ›
Chain: A
Length: 333 amino acids
Theoretical weight: 35.79 KDa
Source organism: Deinococcus radiodurans
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9RVU2 (Residues: 1-323; Coverage: 100%)
Gene name: DR_0930
Sequence domains: Phosphotriesterase family
Structure domains: Metal-dependent hydrolases

Ligands and Environments

2 bound ligands:
Ligand BR 4 x BR
Ligand CO 2 x CO
1 modified residue:
Ligand KCX 1 x KCX

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-D
Spacegroup: P3121
Unit cell:
a: 60.843Å b: 60.843Å c: 207.694Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.182 0.182 0.212
Expression system: Escherichia coli

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