› 2zpq

X-ray diffraction
1.9Å resolution

Crystal structure of anionic trypsin isoform 1 from chum salmon

Released:
DOI: 10.2210/pdb2zpq/pdb
PDB entry 2zpq coloured by chain, front view.
PDB entry 2zpq coloured by chain, side view.
PDB entry 2zpq coloured by chain, top view.
Source organism: Oncorhynchus keta
Primary publication:
A structural comparison of three isoforms of anionic trypsin from chum salmon (Oncorhynchus keta).
Toyota E, Iyaguchi D, Sekizaki H, Tateyama M, Ng KK
Acta Crystallogr D Biol Crystallogr 65 717-23 (2009)
PMID: 19564692

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-183814 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptidase S1 domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 222 amino acids
Theoretical weight: 23.88 KDa
Source organism: Oncorhynchus keta
UniProt:
  • Canonical: Q8AV11 (Residues: 1-222; Coverage: 100%)
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases

Ligands and Environments

3 bound ligands:
Ligand SO4 2 x SO4
Ligand CA 2 x CA
Ligand BEN 2 x BEN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P212121
Unit cell:
a: 65.023Å b: 80.563Å c: 80.821Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.193 0.222

Quick links

Citations

2 citation in other articles

Papain-catalyzed peptide bond formation: enzyme-specific activation with guanidinophenyl esters.
de Beer et al. (2011)
1 more

1 mention without citation

Fish trypsins: potential applications in biomedicine and prospects for production.
Jesús-de la Cruz et al. (2018)