2zpy

X-ray diffraction
2.1Å resolution

Crystal structure of the mouse radxin FERM domain complexed with the mouse CD44 cytoplasmic peptide

Released:
Source organism: Mus musculus
Primary publication:
Structural basis for CD44 recognition by ERM proteins.
J Biol Chem 283 29602-12 (2008)
PMID: 18753140

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-147333 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Radixin Chain: A
Molecule details ›
Chain: A
Length: 312 amino acids
Theoretical weight: 36.93 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P26043 (Residues: 1-310; Coverage: 53%)
Gene name: Rdx
Sequence domains:
Structure domains:
CD44 antigen Chain: B
Molecule details ›
Chain: B
Length: 20 amino acids
Theoretical weight: 2.18 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: P15379 (Residues: 708-727; Coverage: 3%)
Gene names: Cd44, Ly-24

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL38B1
Spacegroup: P212121
Unit cell:
a: 62.7Å b: 66.182Å c: 86.217Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.231 0.231 0.256
Expression systems:
  • Escherichia coli
  • Not provided