› 384d

X-ray diffraction
2.15Å resolution

HYDRATION AND RECOGNITION OF METHYLATED CPG STEPS IN DNA

Released:
DOI: 10.2210/pdb384d/pdb
PDB entry 384d coloured by chain, front view.
PDB entry 384d coloured by chain, side view.
PDB entry 384d coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Hydration and recognition of methylated CpG steps in DNA.
Mayer-Jung C, Moras D, Timsit Y
EMBO J 17 2709-18 (1998)
PMID: 9564052

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-116042 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
5'-D(*CP*(5CM)P*GP*CP*(5CM)P*GP*GP*(5CM)P*GP*G)-3' Chains: A, B
Molecule details ›
Chains: A, B
Length: 10 nucleotides
Theoretical weight: 3.09 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand MG 1 x MG
1 modified residue:
Ligand 5CM 6 x 5CM

Experiments and Validation Details

Entry percentile scores
X-ray source: LURE BEAMLINE DW32
Spacegroup: P61
Unit cell:
a: 54.9Å b: 54.9Å c: 45.6Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.166 0.166 not available
Expression system: Not provided

Quick links

Citations

6 review citations

Evolving insights on how cytosine methylation affects protein-DNA binding.
Dantas Machado et al. (2015)
5 more

2 mentions without citation

Exploring DNA structure with Cn3D.
Porter et al. (2007)
1 more