› 3ag0

X-ray diffraction
2.6Å resolution

Crystal structure of carbonmonoxy human cytoglobin

Released:
DOI: 10.2210/pdb3ag0/pdb
PDB entry 3ag0 coloured by chain, front view.
PDB entry 3ag0 coloured by chain, side view.
PDB entry 3ag0 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the carbon monoxide complex of human cytoglobin.
Makino M, Sawai H, Shiro Y, Sugimoto H
Proteins 79 1143-53 (2011)
PMID: 21254233

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186754 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytoglobin Chain: A
Molecule details ›
Chain: A
Length: 192 amino acids
Theoretical weight: 21.58 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8WWM9 (Residues: 1-190; Coverage: 100%)
Gene names: CYGB, STAP
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments

2 bound ligands:
Ligand HEM 1 x HEM
Ligand CMO 1 x CMO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P212121
Unit cell:
a: 36.198Å b: 43.977Å c: 94.019Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.215 0.215 0.248
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Mammalian iron homeostasis in health and disease: uptake, storage, transport, and molecular mechanisms of action.
Lawen et al. (2013)
5 more

4 mentions without citation

The role of globins in cardiovascular physiology.
Keller et al. (2022)
3 more