Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- GPCR, family 2, calcitonin receptor family
- GPCR, family 2, extracellular hormone receptor domain
- GPCR, family 2, calcitonin gene-related peptide, type 1 receptor
- GPCR family 2, extracellular hormone receptor domain superfamily
- Receptor activity modifying protein
- GPCR, family 2, secretin-like, conserved site
- RAMP domain superfamily
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Adrenomedullin receptor AM1 complex (preferred)
PDBe Complex ID:
PDB-CPX-130171 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Receptor activity-modifying protein 2
Molecule details ›
Chain: A
Length: 91 amino acids
Theoretical weight: 10.58 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli cell-free system
UniProt:
Sequence domains: Receptor activity modifying family
Structure domains: Receptor activity modifying family
Length: 91 amino acids
Theoretical weight: 10.58 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli cell-free system
UniProt:
- Canonical:
O60895 (Residues: 56-139; Coverage: 63%)
Sequence domains: Receptor activity modifying family
Structure domains: Receptor activity modifying family
Calcitonin gene-related peptide type 1 receptor
Molecule details ›
Chain: B
Length: 121 amino acids
Theoretical weight: 14.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli cell-free system
UniProt:
Sequence domains: Hormone receptor domain
Structure domains: GPCR, family 2, extracellular hormone receptor domain
Length: 121 amino acids
Theoretical weight: 14.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli cell-free system
UniProt:
- Canonical: Q16602 (Residues: 23-136; Coverage: 26%)
Sequence domains: Hormone receptor domain
Structure domains: GPCR, family 2, extracellular hormone receptor domain
