Function and Biology Details
Reaction catalysed:
Cleavage of gelatin type I and collagen types IV, V, VII, X. Cleaves the collagen-like sequence Pro-Gln-Gly-|-Ile-Ala-Gly-Gln.
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138355 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
72 kDa type IV collagenase
Molecule details ›
Chain: A
Length: 167 amino acids
Theoretical weight: 18.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Matrixin
Structure domains: Collagenase (Catalytic Domain)
Length: 167 amino acids
Theoretical weight: 18.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P08253 (Residues: 110-450; Coverage: 27%)
Sequence domains: Matrixin
Structure domains: Collagenase (Catalytic Domain)
Soluble APP-beta
Molecule details ›
Chain: B
Length: 10 amino acids
Theoretical weight: 1.08 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 10 amino acids
Theoretical weight: 1.08 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P05067 (Residues: 586-595; Coverage: 1%)
