› 3b0i

X-ray diffraction
1.8Å resolution

Crystal structure of recombinant human alpha lactalbumin

Released:
DOI: 10.2210/pdb3b0i/pdb
PDB entry 3b0i coloured by chain, front view.
PDB entry 3b0i coloured by chain, side view.
PDB entry 3b0i coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural insights into the stability perturbations induced by N-terminal variation in human and goat α-lactalbumin.
Makabe K, Nakamura T, Kuwajima K
Protein Eng Des Sel 26 165-70 (2013)
PMID: 23155056

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132931 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-lactalbumin Chain: A
Molecule details ›
Chain: A
Length: 124 amino acids
Theoretical weight: 14.22 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P00709 (Residues: 20-142; Coverage: 100%)
Gene names: LALBA, LYZL7
Sequence domains: C-type lysozyme/alpha-lactalbumin family
Structure domains: Lysozyme

Ligands and Environments

2 bound ligands:
Ligand CA 1 x CA
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-5A
Spacegroup: P21
Unit cell:
a: 31.702Å b: 33.156Å c: 46.148Å
α: 90° β: 104.09° γ: 90°
R-values:
R R work R free
0.212 0.209 0.256
Expression system: Escherichia coli

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