› 3b5h

X-ray diffraction
2.8Å resolution

Crystal structure of the extracellular portion of HAb18G/CD147

Released:
DOI: 10.2210/pdb3b5h/pdb
PDB entry 3b5h coloured by chain, front view.
PDB entry 3b5h coloured by chain, side view.
PDB entry 3b5h coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of HAb18G/CD147: implications for immunoglobulin superfamily homophilic adhesion.
Yu XL, Hu T, Du JM, Ding JP, Yang XM, Zhang J, Yang B, Shen X, Zhang Z, Zhong WD, Wen N, Jiang H, Zhu P, Chen ZN
J Biol Chem 283 18056-65 (2008)
PMID: 18430721

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152965 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Basigin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 184 amino acids
Theoretical weight: 20.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P35613 (Residues: 140-321; Coverage: 50%)
Gene names: BSG, UNQ6505/PRO21383
Sequence domains: Immunoglobulin domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand ACT 1 x ACT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NW12A
Spacegroup: P41212
Unit cell:
a: 126.481Å b: 126.481Å c: 169.926Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.245 0.243 0.294
Expression system: Escherichia coli

Quick links

Citations

22 review citations

The biological function and clinical utilization of CD147 in human diseases: a review of the current scientific literature.
Xiong et al. (2014)
21 more

32 mentions without citation

Tumor markers as an entry for SARS-CoV-2 infection?
Xia et al. (2020)
31 more