3b6u

X-ray diffraction
1.8Å resolution

Crystal structure of the motor domain of human kinesin family member 3B in complex with ADP

Released:
Source organism: Homo sapiens
Entry authors: Zhu H, Shen Y, Tempel W, Landry R, Arrowsmith CH, Edwards AM, Sundstrom M, Weigelt J, Bochkarev A, Park H, Structural Genomics Consortium (SGC)

Function and Biology Details

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-127280 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kinesin-like protein KIF3B, N-terminally processed Chains: A, B
Molecule details ›
Chains: A, B
Length: 372 amino acids
Theoretical weight: 41.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O15066 (Residues: 6-359; Coverage: 47%)
Gene names: KIAA0359, KIF3B
Sequence domains: Kinesin motor domain
Structure domains: Kinesin motor domain

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E
Spacegroup: P21
Unit cell:
a: 58.731Å b: 95.852Å c: 63.883Å
α: 90° β: 92.61° γ: 90°
R-values:
R R work R free
0.192 0.191 0.233
Expression system: Escherichia coli