› 3b94

X-ray diffraction
2.5Å resolution

Crystal structure of human GITRL

Released:
DOI: 10.2210/pdb3b94/pdb
PDB entry 3b94 coloured by chain, front view.
PDB entry 3b94 coloured by chain, side view.
PDB entry 3b94 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Song XM, Zhou ZC

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193993 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tumor necrosis factor ligand superfamily member 18 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 133 amino acids
Theoretical weight: 14.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9UNG2 (Residues: 50-177; Coverage: 72%)
Gene names: AITRL, GITRL, TL6, TNFSF18, UNQ149/PRO175
Structure domains: Jelly Rolls

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P63
Unit cell:
a: 141.943Å b: 141.943Å c: 47.211Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.221 0.217 0.276
Expression system: Escherichia coli BL21

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