› 3bct

X-ray diffraction
2.1Å resolution

THE ARMADILLO REPEAT REGION FROM MURINE BETA-CATENIN

Released:
DOI: 10.2210/pdb3bct/pdb
PDB entry 3bct coloured by chain, front view.
PDB entry 3bct coloured by chain, side view.
PDB entry 3bct coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Three-dimensional structure of the armadillo repeat region of beta-catenin.
Huber AH, Nelson WJ, Weis WI
Cell 90 871-82 (1997)
PMID: 9298899

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-169699 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Catenin beta-1 Chain: A
Molecule details ›
Chain: A
Length: 470 amino acids
Theoretical weight: 51.78 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q02248 (Residues: 193-662; Coverage: 60%)
Gene names: Catnb, Ctnnb1
Sequence domains: Armadillo/beta-catenin-like repeat
Structure domains: Leucine-rich Repeat Variant

Ligands and Environments

2 bound ligands:
Ligand CL 1 x CL
Ligand URE 8 x URE
1 modified residue:
Ligand MSE 13 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL1-5
Spacegroup: C2221
Unit cell:
a: 64.1Å b: 102Å c: 187Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.229 0.229 0.26
Expression system: Escherichia coli

Quick links

Citations

116 review citations

Wnt/β-catenin signaling and disease.
Clevers et al. (2012)
115 more

15 mentions without citation

Overview of protein structural and functional folds.
Sun et al. (2004)
14 more