› 3bdl

X-ray diffraction
1.9Å resolution

Crystal structure of a truncated human Tudor-SN

Released:
DOI: 10.2210/pdb3bdl/pdb
PDB entry 3bdl coloured by chain, front view.
PDB entry 3bdl coloured by chain, side view.
PDB entry 3bdl coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural and functional insights into human Tudor-SN, a key component linking RNA interference and editing.
Li CL, Yang WZ, Chen YP, Yuan HS
Nucleic Acids Res 36 3579-89 (2008)
PMID: 18453631

Function and Biology Details

Reaction catalysed: 
Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotide end-products
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-181614 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Staphylococcal nuclease domain-containing protein 1 Chain: A
Molecule details ›
Chain: A
Length: 570 amino acids
Theoretical weight: 64.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7KZF4 (Residues: 340-888; Coverage: 60%)
Gene names: SND1, TDRD11
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand CIT 4 x CIT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL12B2
Spacegroup: C2
Unit cell:
a: 97.405Å b: 91.929Å c: 88.042Å
α: 90° β: 91.26° γ: 90°
R-values:
R R work R free
0.175 0.175 0.209
Expression system: Escherichia coli

Quick links

Citations

15 review citations

Deciphering arginine methylation: Tudor tells the tale.
Chen et al. (2011)
14 more

4 mentions without citation

Structural and functional insights into human Tudor-SN, a key component linking RNA interference and editing.
Li et al. (2008)
3 more