3bes

X-ray diffraction
2.2Å resolution

Structure of a Poxvirus ifngbp/ifng Complex

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero octamer
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-134404 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Interferon gamma Chain: L
Molecule details ›
Chain: L
Length: 139 amino acids
Theoretical weight: 16.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01579 (Residues: 24-161; Coverage: 97%)
Gene name: IFNG
Sequence domains: Interferon gamma
Structure domains: Growth Hormone; Chain: A;
Interferon gamma receptor D2 domain-containing protein Chain: R
Molecule details ›
Chain: R
Length: 250 amino acids
Theoretical weight: 28.72 KDa
Source organism: Ectromelia virus
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: Q66793 (Residues: 17-266; Coverage: 94%)
Gene names: C4R, EVHE185, EVI185, EVM1185, EVM4185, EVM5185, EVMH185, EVMK185, IFNGR
Sequence domains: Interferon gamma receptor (IFNGR1), D2 domain
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: I222
Unit cell:
a: 92.63Å b: 119.13Å c: 184.74Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.219 0.219 0.245
Expression systems:
  • Escherichia coli
  • Drosophila melanogaster