3bk3

X-ray diffraction
2.7Å resolution

Crystal structure of the complex of BMP-2 and the first Von Willebrand domain type C of Crossveinless-2

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero tetramer
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-146276 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Bone morphogenetic protein 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 114 amino acids
Theoretical weight: 12.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P12643 (Residues: 283-396; Coverage: 31%)
Gene names: BMP2, BMP2A
Sequence domains: Transforming growth factor beta like domain
Structure domains: Cystine-knot cytokines
Crossveinless 2 Chains: C, D
Molecule details ›
Chains: C, D
Length: 67 amino acids
Theoretical weight: 7.19 KDa
Source organism: Danio rerio
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5D734 (Residues: 28-93; Coverage: 10%)
Gene names: bmper, cvl2, id:ibd5071
Structure domains: Defensin A-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: I41
Unit cell:
a: 83.75Å b: 83.75Å c: 139.85Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.205 0.203 0.245
Expression system: Escherichia coli BL21(DE3)