3bn3

X-ray diffraction
2.1Å resolution

crystal structure of ICAM-5 in complex with aL I domain

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-149033 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Integrin alpha-L Chain: A
Molecule details ›
Chain: A
Length: 180 amino acids
Theoretical weight: 20.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P20701 (Residues: 154-332; Coverage: 16%)
Gene names: CD11A, ITGAL
Sequence domains: von Willebrand factor type A domain
Structure domains: von Willebrand factor, type A domain
Intercellular adhesion molecule 5 Chain: B
Molecule details ›
Chain: B
Length: 196 amino acids
Theoretical weight: 22.12 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: Q9UMF0 (Residues: 32-227; Coverage: 22%)
Gene names: ICAM5, TLCN, TLN
Sequence domains: Intercellular adhesion molecule (ICAM), N-terminal domain
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 61.793Å b: 71.507Å c: 143.871Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.191 0.235
Expression systems:
  • Escherichia coli
  • Cricetulus griseus