Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Immunoglobulin-like fold
- Interleukin-13
- Fibronectin type III
- Fibronectin type III superfamily
- Short hematopoietin receptor, family 2, conserved site
- Type I cytokine receptor, cytokine-binding domain
- Interleukin-13 receptor subunit alpha-1, Ig-like domain
- Short hematopoietin receptor, family 1, conserved site
4 more domains
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-150222 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Interleukin-13
Molecule details ›
Chain: A
Length: 127 amino acids
Theoretical weight: 14.14 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Interleukin-13
Structure domains: Growth Hormone; Chain: A;
Length: 127 amino acids
Theoretical weight: 14.14 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P35225 (Residues: 34-73, 74-146; Coverage: 93%)
Sequence domains: Interleukin-13
Structure domains: Growth Hormone; Chain: A;
Soluble interleukin-4 receptor subunit alpha
Molecule details ›
Chain: B
Length: 205 amino acids
Theoretical weight: 23.47 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Interleukin-4 receptor alpha chain, N-terminal
Structure domains: Immunoglobulins
Length: 205 amino acids
Theoretical weight: 23.47 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: P24394 (Residues: 27-227; Coverage: 25%)
Sequence domains: Interleukin-4 receptor alpha chain, N-terminal
Structure domains: Immunoglobulins
Interleukin-13 receptor subunit alpha-1
Molecule details ›
Chain: C
Length: 314 amino acids
Theoretical weight: 36.36 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Structure domains: Immunoglobulins
Length: 314 amino acids
Theoretical weight: 36.36 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: P78552 (Residues: 29-342; Coverage: 77%)
Sequence domains:
Structure domains: Immunoglobulins
