3bs5

X-ray diffraction
2Å resolution

Crystal Structure of hCNK2-SAM/dHYP-SAM Complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-185316 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein aveugle Chain: A
Molecule details ›
Chain: A
Length: 106 amino acids
Theoretical weight: 12.99 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8ML92 (Residues: 1-106; Coverage: 100%)
Gene names: CG30476, ave
Sequence domains: SAM domain (Sterile alpha motif)
Structure domains: Transcription Factor, Ets-1
Connector enhancer of kinase suppressor of ras 2 Chain: B
Molecule details ›
Chain: B
Length: 80 amino acids
Theoretical weight: 9.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8WXI2 (Residues: 5-84; Coverage: 8%)
Gene names: CNK2, CNKSR2, KIAA0902, KSR2
Sequence domains: SAM domain (Sterile alpha motif)
Structure domains: Transcription Factor, Ets-1

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P212121
Unit cell:
a: 48.477Å b: 56.356Å c: 84.04Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.212 0.24
Expression system: Escherichia coli