› 3bxw

X-ray diffraction
2.7Å resolution

Crystal Structure of Stabilin-1 Interacting Chitinase-Like Protein, SI-CLP

Released:
DOI: 10.2210/pdb3bxw/pdb
PDB entry 3bxw coloured by chain, front view.
PDB entry 3bxw coloured by chain, side view.
PDB entry 3bxw coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of human stabilin-1 interacting chitinase-like protein (SI-CLP) reveals a saccharide-binding cleft with lower sugar-binding selectivity.
Meng G, Zhao Y, Bai X, Liu Y, Green TJ, Luo M, Zheng X
J Biol Chem 285 39898-904 (2010)
PMID: 20724479

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189777 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chitinase domain-containing protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 393 amino acids
Theoretical weight: 45.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9BWS9 (Residues: 1-393; Coverage: 100%)
Gene names: CHID1, GL008, PSEC0104, SB139
Sequence domains: Glycosyl hydrolases family 18
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P3221
Unit cell:
a: 100.11Å b: 100.11Å c: 249.97Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.243 0.222 0.253
Expression system: Escherichia coli

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Citations

6 review citations

Fascinating Fasciclins: A Surprisingly Widespread Family of Proteins that Mediate Interactions between the Cell Exterior and the Cell Surface.
Seifert et al. (2018)
5 more

4 mentions without citation

Structure of human stabilin-1 interacting chitinase-like protein (SI-CLP) reveals a saccharide-binding cleft with lower sugar-binding selectivity.
Meng et al. (2010)
3 more